Monthly Archives: December 2013

Nanoparticles: a pill instead of an injection

A new advance in the use of nanoparticles to deliver medicine or other therapeutics orally is described in a short summary in a Wall Street Journal article or a longer, more detailed news release from MIT.  Not surprisingly Professor Robert Langer is an author on the paper appearing in the Nov. 27 online edition of Science Translational Medicine.  In a classic example of looking to nature to show the way, the researchers looked at previous work on how babies absorb antibodies from their mothers’ milk, and then built nanoparticles that are selectively passed through the intestinal barrier using protein coats that are recognized by receptor sites in the intestinal lining.

The research was funded by a Koch-Prostate Cancer Foundation Award in Nanotherapeutics; the National Cancer Institute Center of Cancer Nanotechnology Excellence at MIT-Harvard; a National Heart, Lung, and Blood Institute Program of Excellence in Nanotechnology Award; and the National Institute of Biomedical Imaging and Bioengineering.